Silymarin Ameliorates Acrylamide-Induced Hyperlipidemic Cardiomyopathy in Male Rats

Table 3

Effect of silymarin on severity of myocardial lesions in rats treated with acrylamide.

Histopathological changes	Control	AA	SIL	AA+SIL
Disruption of cardiac muscle organization	−	+++	−	++
Necrosis	−	+++	−	++
Inflammatory cell infiltrate	−	++	−	+
Nuclear pyknosis	−	++	−	+

Scores obtained from tissue sections of five rats/group. Scores: –(normal), + (mild change), ++ (moderate), and +++ (severe levels).