Research Article
Identification of Upregulated HNRNPs Associated with Poor Prognosis in Pancreatic Cancer
Table 1
Cox regression multivariate analysis in TCGA-PAAD.
| Group | Num | Hazard ration (95%CI) | P value |
| Univariate cox model |
| Sex | Female | 80 | 1 | | Male | 98 | 0.809(0.537-1.219) | 0.312 | Age(year) | <65 | 81 | 1 | | ≥65 | 97 | 1.396(0.918-2.121) | 0.118 | TNM stage | I/IIA | 49 | 1 | | IIB/III/IV | 127 | 2.050(1.217-3.452) | 0.007 | Tumor invasion | T1/2 | 31 | 1 | | T3/4 | 145 | 2.022(1.072-3.815) | 0.030 | Histologic grade | G1 | 31 | 1 | | G2 | 95 | 1.956(1.006-3.803) | 0.048 | G3 | 48 | 2.622(1.303-5.279) | 0.007 | G4 | 2 | 1.650(0.211-12.885) | 0.633 | Lymph nodes metastasis | N0 | 50 | 1 | | N1 | 123 | 2.154(1.282-3.618) | 0.004 | HNRNPL expression | Low expression | 89 | 1 | | High expression | 89 | 1.861(1.222-2.833) | 0.004 |
| Multivariate cox model |
| TNM stage | I/IIA | 49 | 1 | | IIB/III/IV | 127 | 1.772(1.015-3.093) | 0.044 | Histologic grade | G1 | 31 | 1 | | G2 | 95 | 1.667(0.856-3.246) | 0.133 | G3 | 48 | 2.082(1.033-4.197) | 0.040 | G4 | 2 | 1.300(0.166-10.203) | 0.802 | HNRNPL expression | Low expression | 89 | 1 | | High expression | 89 | 1.171(1.102-2.665) | 0.017 |
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