Keap1 Cystenine 151 as a Potential Target for Artemisitene-Induced Nrf2 Activation

Figure 4

ATT is effective at low doses. Immunoblots showing Nrf2 levels in cells treated with 0.05% DMSO (lanes 1): 1 μM, 3 μM, and 5 μM ATT (a); 5 μM, 10 μM, and 25 μM sulforaphane (b); or 25 μM, 50 μM, and 100 μM tBHQ (c). (d) Scatter plot showing the dose responsiveness in the differentially treated cells.

(a)

(b)

(c)

(d)