Peptide Mix from Olivancillaria hiatula Interferes with Cell-to-Cell Communication in Pseudomonas aeruginosa

Figure 2

(a) Growth curve of Pseudomonas aeruginosa ATCC 4853 in the absence (GC) and presence of varying concentrations of peptide mix (MIC, 1/32 MIC). After 24 hours of growth, Pseudomonas aeruginosa absorptions (OD₆₀₀) were similar, with no significant difference between all treated cells relative to the untreated control. (b) Cell density of Pseudomonas aeruginosa ATCC 4853 cultivated in the absence (GC) and presence of sub-MICs of peptide mix. Cell density was recorded after 24 hours of growth. Mean values of 3 independent experiments and their standard deviations are shown. When compared with the untreated control (GC), no significant difference () was observed. Cell density for MIC treatment was significantly different () from that of sub-MIC-treated groups (MIC, minimum inhibitory concentration; GC, growth control).

(a)

(b)