Decreased Expression of Cannabinoid Receptors in the Eutopic and Ectopic Endometrium of Patients with Adenomyosis

Figure 1

Immunohistochemical staining of CB1. (a) Normal endometrium in the proliferative phase. (b) Normal endometrium in the secretory phase. (c) Quantitative analysis of the mean optical density (MOD) between proliferative phase and secretory phase in normal endometrium. (d) Eutopic endometrium in the proliferative phase. (e) Eutopic endometrium in the secretory phase. (f) Quantitative analysis of MOD values between proliferative phase and secretory phase in eutopic endometrium. (g) Ectopic endometrium in the proliferative phase. (h) Ectopic endometrium in the secretory phase. (i) Quantitative analysis of MOD values between proliferative phase and secretory phase in ectopic endometrium. (j) and (k) Quantitative analysis of MOD values among normal endometrium, eutopic endometrium and ectopic endometrium in proliferative phase and secretory phase, respectively. All magnifications of the micrographs were × 400. Scale bars represent 5 μm. The error bars on all histograms represent the standard deviation. , < 0.05; , < 0.01; , < 0.001.

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