Review Article

Prognostic Models for Predicting Overall Survival in Patients with Primary Gastric Cancer: A Systematic Review

Table 2

Final predictors included in the models.

CategoryNumber of predictorsNumber of predictors selected multiple timesPredictors selected multiple timesa

Patient219Age, sex, ethnicity, performance score, year of diagnosis, family history, smoking, residency, and addiction to opium

Disease status3421T stage, N stage, TNM stage, tumor site, tumor size, differentiation, metastasis, histologic type, Lauren type, LN ratio, lymphovascular invasion, bone metastasis, Borrmann type, liver metastasis, number of metastasis sites, lung metastasis, number of examined LN, metastasis LN, perineural invasion, LODDS, and TTP after chemotherapy

Biomarker11619CEA, NLR, ALP, albumin, bilirubin, CA199, Hb, CES1, IS, LDH, LNR:ART, lymphocyte count, MGAT5, mGPS, NPTM, platelet, sodium, TNFRSF11A, and WBC

Treatment96Chemotherapy, gastrectomy, lymphedenectomy, resection margin, extent of resection, and radiotherapy

aThe table lists only the predictors that have been included more than once. LN: lymph node. LODDS: log odds of positive LN. CEA: carcinoembryonic antigen. NLR: neutrophil/lymphocyte ratio. ALP: alkaline phosphatase. Hb: hemoglobin. MGAT5: β1, 6-N-acetylglucosaminyltransferase-5. mGPS: modified Glasgow Prognostic Score. CA199: cancer antigen 199. NPTM: number of positive tumor markers (cancer antigen 125, CA199, CEA). WBC: white blood cell. TTP: time to progression.