Multifunctional TRPV1 Ion Channels in Physiology and Pathology with Focus on the Brain, Vasculature, and Some Visceral Systems

<p>General outline of TRPV1 channels’ role in signaling pathways that regulate vascular and visceral functions. TRPV1: transient receptor potential channel vanilloid family type 1; AMPK: AMP activated protein kinase; CGRP: calcitonin gene-related peptide, 20-HETE: 20-hydroxy-5, 8, 11, 14-eicosatetraenoic acid; NOS: NO synthase; PKA: protein kinase A; PPR-<i>γ</i>: peroxisome proliferator-activated receptor-<i>γ</i>; SP: substance P; and VIP: vasoactive intestinal polypeptide.</p>

BioMed Research International

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Figure 1: Multifunctional TRPV1 Ion Channels in Physiology and Pathology with Focus on the Brain, Vasculature, and Some Visceral Systems 