Focused Ultrasound Effects on Osteosarcoma Cell Lines

Figure 1

Multiwell plate setups analysed in MRgFUS experiments: (a) Flat-setup where 24 wells were previously filled with 0.5 ml of agar gel (the figure is not in scale: the transducer array is depicted nearer to the well and smaller than in the reality); (b) V-setup, where the wells were previously filled with 2.5 ml of agar gel and a V-bottom shape was realized applying a modified 24 polystyrene lid (c) on the plate until the agar had solidified. In the V-setup, cells were concentrated in a reduced volume for better uniformity of exposure to the acoustic field. (d) and (e) images represent the MR axial and coronal sections, respectively, of the multiwell plate prepared with the V-setup. Note that panel schemes are not in scale.

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