[Retracted] Second-Generation Histamine H1 Receptor Antagonists Suppress Delayed Rectifier K⁺-Channel Currents in Murine Thymocytes

Figure 3

Effects of second-generation antihistamines on the degree of inactivation of Kv1.3 channel currents. The effects of 100 μM cetirizine (a), 100 μM fexofenadine (b), 100 μM azelastine (c), and 10 μM terfenadine (d) on the ratio of the pulse-end currents, which were considered as a “steady-state” currents (Iss), to the peak currents (Ip) obtained from the current traces at the voltage-step of 80 mV. ^# p < 0.05 vs. before the drug application. Values are means ± SEM (cetirizine, n = 5; fexofenadine, n = 5; azelastine, n = 5; terfenadine, n = 4). Differences were analyzed by ANOVA followed by Dunnett’s or Student’s test.

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