Research Article
[Retracted] Second-Generation Histamine H1 Receptor Antagonists Suppress Delayed Rectifier K+-Channel Currents in Murine Thymocytes
Table 1
Summary of changes in membrane capacitance after application of cetirizine, fexofenadine, azelastine, and terfenadine.
| Agents | n | Cm before drug application | Cm after drug application | ΔCm (fF) | (pF) | (pF) |
| External Solution | 6 | 3.48 ± 0.30 | 3.41 ± 0.29 | 70.0 ± 29.1 | 100 μM Cetirizine | 5 | 2.66 ± 0.28 | 2.61 ± 0.27 | 86.0 ± 11.2 | 100 μM Fexofenadine | 6 | 3.41 ± 0.43 | 3.36 ± 0.44 | 65.0 ± 14.8 | 100 μM Azelastine | 6 | 4.34 ± 0.73 | 3.63 ± 0.54♯ | 706 ± 228 | 10 μM Terfenadine | 5 | 2.93 ± 0.42 | 2.67 ± 0.39♯ | 267 ± 74.4 |
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Values are means ± SEM. Cm = membrane capacitance. #p < 0.05 vs. Cm before drug application.
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