Clinical Efficacy of Extracorporeal Cardiopulmonary Resuscitation for Adults with Cardiac Arrest: Meta-Analysis with Trial Sequential Analysis

Figure 2

(a) Forest plot of studies reporting 30-day survival outcome. (b) Random-effect model of trial sequential analysis for 30-day survival outcome. Type 1 error is =5%; A diversity-adjusted information size of 3699 participants calculated on the basis of a survival rate of 17.5% in the CCPR group, 20% increase in outcome, α = 5% (two sided), β = 20%, and = 30%. Complete blue line represents cumulative Z-curve, which crossed conventional boundary (dashed red line) and the trial sequential monitoring boundary (dashed gray line).

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