Review Article
Clinical Efficacy of Extracorporeal Cardiopulmonary Resuscitation for Adults with Cardiac Arrest: Meta-Analysis with Trial Sequential Analysis
Table 1
Characteristics of the studies included in the meta-analysis.
(a) |
| Study(year) | Nation | Study design | OHCA/IHCA | Patients (N.) | Male (%) | Mean age ECPR/CCPR (years) |
| Blumenstein (2015) | Germany | CS and PSM | IHCA | 104 | 56.7 | 72/73 | Chen (2008) | Taiwan | CS and PSM | IHCA | 92 | 85.9 | 57/55 | Choi (2016) | Korea | CS and PSM | OHCA | 640 | 81 | 56/58 | Chou (2014) | Taiwan | CS | IHCA | 66 | 86.4 | 60.5/69.6 | Kim (2014) | Korea | CS and PSM | OHCA | 104 | 76.5 | 54/54 | Lee (2015) | Korea | CS | IHCA and OHCA | 955 | 64.9 | 59.0/63.5 | Lin (2010) | Taiwan | CS and PSM | IHCA | 54 | 81.5 | 59/60 | Maekawa (2013) | Japan | CS and PSM | OHCA | 48 | 79.2 | 57/57 | Sakatomo (2014) | Japan | CS | OHCA | 454 | 89.6 | 56.3/58.1 | Schober (2017) | Austria | CS | OHCA | 239 | 74 | 46/60 | Shin (2011) | Korea | CS and PSM | IHCA | 90 | 64.7 | 63.5/61.5 | Shin (2013) | Korea | CS and PSM | IHCA | 120 | 64.2 | 60.8/60.5 | Siao (2015) | Taiwan | CS | IHCA and OHCA | 60 | 76.7 | 54.6/60.3 |
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(b) |
| Study(year) | AMI ECPR/CCPR (%) | ROSC rate ECPR/CCPR (%) | CPR duration ECPR/CCPR (min) | Time-to-ECOM (min) | Mortality (%) |
| Blumenstein (2015) | 28.9/36.6 | NR/NR | 33(19-47)/ 37(30-45)# | NR | 77.9% | Chen (2008) | 61/72 | 42/24 | 53 (41)/47 (33) | NR | 75% | Choi (2016) | NR/NR | NR/NR | 35(19-54.5)/28(15-37)# | NR | 83.3% | Chou (2014) | 100/100 | 100/52.1 | NR/NR | 59.7±34.1 | 69.7% | Kim (2014) | 84.6/88.5 | 30.8/32.7 | 62.5(49-88)/ 60.5(40-83.5)# | 68.5 (32-132)# | 80.8% | Lee (2015) | NR/NR | 86.4/73.3 | 43(21-60)/30(15-48)# | NR | 85.5% | Lin (2010) | 65.5/73.0 | 100/100 | 41.8 (19.8)/40.0 (26.4) | NR | 70.4% | Maekawa (2013) | NR/NR | 4.2/12.5 | 49(43-66)/ 52(43-65)# | NR | 75% | Sakatomo (2014) | 63.5/59.3 | NR/NR | NR/NR | NR | NR | Schober (2017) | NR/NR | 57/38 | 97(79-147)/ 77(58-95)# | 55(48-65)# | NR | Shin (2011) | 48.8/48.8 | 35/21 | 37.9(19.3)/36.8(19.3) | NR | 77.8% | Shin (2013) | 43.3/35.0 | 75/48.3 | 38.8(20.7)/38.1(21.0) | NR | 68.9% | Siao (2015) | 60/40 | 95/47.5 | NR/NR | NR | 65% |
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Data are reported as mean ± standard deviation or median (interquartile range); #: median (IQR); : mean (SD). Abbreviations: OHCA=out-of-hospital cardiac arrest, IHCA=in-hospital cardiac arrest, N=number, NR=not reported, ECPR=extracorporeal cardiopulmonary resuscitation, CCPR=conventional cardiopulmonary resuscitation, AMI= acute myocardial infarction, ROSC=return of spontaneous circulation, CPR= cardiopulmonary resuscitation, CS=cohort study, PSM= propensity score matching, and ECOM= extracorporeal membrane oxygenation. |