BioMed Research International / 2019 / Article / Tab 1

Review Article

Clinical Efficacy of Extracorporeal Cardiopulmonary Resuscitation for Adults with Cardiac Arrest: Meta-Analysis with Trial Sequential Analysis

Table 1

Characteristics of the studies included in the meta-analysis.
(a)

Study(year)NationStudy designOHCA/IHCAPatients
(N.)
Male
(%)
Mean age ECPR/CCPR
(years)

Blumenstein (2015)GermanyCS and PSMIHCA10456.772/73
Chen (2008)TaiwanCS and PSMIHCA9285.957/55
Choi (2016)KoreaCS and PSMOHCA6408156/58
Chou (2014)TaiwanCSIHCA6686.460.5/69.6
Kim (2014)KoreaCS and PSMOHCA10476.554/54
Lee (2015)KoreaCSIHCA and OHCA95564.959.0/63.5
Lin (2010)TaiwanCS and PSMIHCA5481.559/60
Maekawa (2013)JapanCS and PSMOHCA4879.257/57
Sakatomo (2014)JapanCSOHCA45489.656.3/58.1
Schober (2017)AustriaCSOHCA2397446/60
Shin (2011)KoreaCS and PSMIHCA9064.763.5/61.5
Shin (2013)KoreaCS and PSMIHCA12064.260.8/60.5
Siao (2015)TaiwanCSIHCA and OHCA6076.754.6/60.3

(b)

Study(year)AMI
ECPR/CCPR
(%)
ROSC rate
ECPR/CCPR
(%)
CPR duration
ECPR/CCPR
(min)
Time-to-ECOM
(min)
Mortality
(%)

Blumenstein (2015)28.9/36.6NR/NR33(19-47)/
37(30-45)#
NR77.9%
Chen (2008)61/7242/2453 (41)/47 (33)NR75%
Choi (2016)NR/NRNR/NR35(19-54.5)/28(15-37)#NR83.3%
Chou (2014)100/100100/52.1NR/NR59.7±34.169.7%
Kim (2014)84.6/88.530.8/32.762.5(49-88)/
60.5(40-83.5)#
68.5
(32-132)#
80.8%
Lee (2015)NR/NR86.4/73.343(21-60)/30(15-48)#NR85.5%
Lin (2010)65.5/73.0100/10041.8 (19.8)/40.0 (26.4)NR70.4%
Maekawa (2013)NR/NR4.2/12.549(43-66)/
52(43-65)#
NR75%
Sakatomo (2014)63.5/59.3NR/NRNR/NRNRNR
Schober (2017)NR/NR57/3897(79-147)/
77(58-95)#
55(48-65)#NR
Shin (2011)48.8/48.835/2137.9(19.3)/36.8(19.3)NR77.8%
Shin (2013)43.3/35.075/48.338.8(20.7)/38.1(21.0)NR68.9%
Siao (2015)60/4095/47.5NR/NRNR65%

Data are reported as mean ± standard deviation or median (interquartile range); #: median (IQR); : mean (SD). Abbreviations: OHCA=out-of-hospital cardiac arrest, IHCA=in-hospital cardiac arrest, N=number, NR=not reported, ECPR=extracorporeal cardiopulmonary resuscitation, CCPR=conventional cardiopulmonary resuscitation, AMI= acute myocardial infarction, ROSC=return of spontaneous circulation, CPR= cardiopulmonary resuscitation, CS=cohort study, PSM= propensity score matching, and ECOM= extracorporeal membrane oxygenation.

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