Identification of Potential Biomarkers in Glioblastoma through Bioinformatic Analysis and Evaluating Their Prognostic Value

Table 2

The GO and KEGG terms enriched by downregulated DEGs.

Category	Term	Count	P-Value
GOTERM_BP_FAT	GO:0007268~synaptic transmission	52	1.62E-31
GOTERM_BP_FAT	GO:0019226~transmission of nerve impulse	54	5.18E-30
GOTERM_BP_FAT	GO:0007267~cell-cell signaling	57	4.96E-21
GOTERM_BP_FAT	GO:0006836~neurotransmitter transport	23	2.20E-18
GOTERM_BP_FAT	GO:0050877~neurological system process	72	3.01E-15
GOTERM_CC_FAT	GO:0045202~synapse	63	1.62E-35
GOTERM_CC_FAT	GO:0044456~synapse part	51	7.00E-32
GOTERM_CC_FAT	GO:0043005~neuron projection	50	4.79E-24
GOTERM_CC_FAT	GO:0008021~synaptic vesicle	25	1.28E-20
GOTERM_CC_FAT	GO:0030054~cell junction	49	1.50E-15
GOTERM_MF_FAT	GO:0022836~gated channel activity	36	6.73E-16
GOTERM_MF_FAT	GO:0005216~ion channel activity	39	3.23E-15
GOTERM_MF_FAT	GO:0015267~channel activity	40	4.98E-15
GOTERM_MF_FAT	GO:0022803~passive transmembrane transporter activity	40	5.43E-15
GOTERM_MF_FAT	GO:0022838~substrate specific channel activity	39	8.74E-15
KEGG_PATHWAY	hsa04080: Neuroactive ligand-receptor interaction	25	3.52E-10
KEGG_PATHWAY	hsa04020: Calcium signaling pathway	21	4.34E-10
KEGG_PATHWAY	hsa04720: Long-term potentiation	9	8.19E-05
KEGG_PATHWAY	hsa04012: ErbB signaling pathway	8	0.00232
KEGG_PATHWAY	hsa04010: MAPK signaling pathway	13	0.010508

BP: biological process; CC: cellular component; MF: molecular function.