Research Article

Cross-platform Data Analysis Reveals a Generic Gene Expression Signature for Microsatellite Instability in Colorectal Cancer

Table 4

Pathway enrichment analysis of the proposed 25-gene expression signature against MSigDB gene collections. MSigDB molecular signatures database.

MsigDB gene set nameadj. p-valueGenes in overlap

Watanabe colon cancer MSI vs MSS down [22]0.005VAV3, ACSL6, GNG4, KRT23
Koinuma colon cancer MSI down [23]0.045AXIN2, MLH1
Sansom WNT pathway require MYC [24]0.045AXIN2, NKD1, ASCL2