Chlorogenic Acid Attenuates Dextran Sodium Sulfate-Induced Ulcerative Colitis in Mice through MAPK/ERK/JNK Pathway

Figure 5

Effect of chlorogenic acid on the expression of MAPK/ERK/ JNK pathway-related proteins in DSS mice. The expression levels of MAPK/ERK/NF-κB pathway-related proteins were detected by IHC and Western blot. IHC assay was performed to detect (a) ERK1/2, p-ERK, p38, p-p38, (b) JNK, p-JNK, p-IκB, and p-p65 of mice in each group (scale bar=50 μm); (c) Western blot assay was performed to detect the expression levels of ERK1/2, p-ERK, p38, p -p38, JNK, p-JNK, p-IκB, and p-p65 protein of mice in each group; indicates P<0.05.

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