BioMed Research International / 2019 / Article / Fig 6

Research Article

Chlorogenic Acid Attenuates Dextran Sodium Sulfate-Induced Ulcerative Colitis in Mice through MAPK/ERK/JNK Pathway

Figure 6

Chlorogenic acid improves DSS-induced ulcerative colitis in mice through MAPK/ERK/JNK signaling pathway. (a) ELISA assays were used to detected IL-1β, IL-6, TNF-α, IL-10, PAF, PGE2, MPO, and SOD expression levels of mice in each group; (b) Western blot assay was performed to detect the expression levels of Bax, Bcl-2, and cleaved-Caspase3 protein of mice in each group; (c) Western blot assay was performed to detect the expression levels of ERK1/2, p-ERK, p38, p -p38, JNK, p-JNK, p-IκB, and p-p65 protein of mice in each group; indicates P<0.05.

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