TY - JOUR A2 - Pabelick, Christina AU - Li, Zhao AU - Xu, Li AU - Zheng, Jinwei AU - Wang, Qingxiu PY - 2019 DA - 2019/04/17 TI - Comparison of Intravenous Dexmedetomidine versus Esmolol for Attenuation of Hemodynamic Response to Tracheal Intubation after Rapid Sequence Induction: A Systematic Review and Meta-Analysis SP - 6791971 VL - 2019 AB - The present study aims to investigate whether intravenous dexmedetomidine shows superiority to esmolol for hemodynamic response to tracheal intubation after rapid sequence induction. In the present meta-analysis, PubMed, EMBASE, and the Cochrane Library were searched for trials comparing dexmedetomidine with esmolol for the attenuation of the hemodynamic response to intubation. Ten trials were selected in the present meta-analysis. Compared to esmolol, the use of dexmedetomidine maintains stable heart rates (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP), and mean arterial pressure (MAP) at 1 min, 3 min, and 5 min after tracheal intubation. Dexmedetomidine causes less hemodynamic response to tracheal intubation after rapid sequence induction compared with esmolol. SN - 2314-6133 UR - https://doi.org/10.1155/2019/6791971 DO - 10.1155/2019/6791971 JF - BioMed Research International PB - Hindawi KW - ER -