Dihydromyricetin Ameliorates Cardiac Ischemia/Reperfusion Injury through Sirt3 Activation
DHM improved mitochondrial function after H/R. (a, b) Representative blots of Sirt3. (c) The morphology of mitochondria (yellow arrow) in cardiomyocytes. (d) JC-1 aggregates label normal mitochondria with polarized inner mitochondrial membranes (Red). JC-1 monomers represent DYm dissipation (Green). (e) Quantification of the DYm (n=50 in each group). Scale bars= 20 um. Mean ± SEM, P<0.05 vs Con; #P<0.05 vs Ad-sh-Sirt3; §P < 0.05 vs H/R; P<0.05 vs Ad-sh-Sirt3+H/R; &P<0.05 vs H/R+DHM.
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