Antibacterial Effect of Curcumin against Clinically Isolated Porphyromonas gingivalis and Connective Tissue Reactions to Curcumin Gel in the Subcutaneous Tissue of Rats

Table 2

Mean and frequency distribution of the score of inflammation severity in different groups at three experimental periods.

Period	Group	Score of inflammation severity
		Mean ± SD	value (ANOVA)	None (%)	Mild (%)	Moderate (%)	Severe (%)	value
7 days	Control	1.8 ± 0.4	0.074	0	20	80	0	≤0.001
	Tetracycline	1.6 ± 0.5		0	40	60	0
	Curcumin	2.4 ± 0.5		0	0	60	40
30 days	Control	1.4 ± 0.9	0.016	20	20	60	0	≤0.001
	Tetracycline	0.8 ± 0.4		20	80	0	0
	Curcumin	1.8 ± 0.4		0	20	80	0
60 days	Control	0.4 ± 0.5	0.335	60	40	0	0	≤0.001
	Tetracycline	0.2 ± 0.4		80	20	0	0
	Curcumin	0		100	0	0	0

value ≤0.05 was considered significant.