Hemoglobinopathies in the North of Morocco: Consanguinity Pilot Study

Table 6

Comparison of the consanguinity profile of Moroccan population.

Type of study	Population study	Reference, Year (N)	Consanguinity rate (%)	FI	FC + DFC (%)	DSC + SC (%)
Regional	Families with hemoglobinopathies in Northern Morocco	This study, 2018 (197)	50.25	0.02	36.04	14.21
Regional	Northern Morocco	This study, 2018 (900)	29.66	0.01	25.44	4.22
Regional	Tangier-Tetouan region	Hardouz et al., 2014 (160) [6]	39.4	0.02	30	5.6
National	Families with autosomal recessive diseases in Rabat	Cherkaoui Jaouad et al., 2009 (176) [12]	59.09	0.03	43.18	11.93
National	All Moroccan regions	Bouazzaoui, 1994 (4773) [11]	19.90	0.008	No data	No data
Regional	Different regions	Talbi, 2007 (873) [7]	22.79	0.008	9.69	4.93

FI = coefficient of inbreeding; DFC = double first cousin; FC = first cousin; DSC = double second cousin; SC = second cousin. Double second cousins are not included in this prevalence.