Functional Variant rs4442975 Modulating FOXA1 Binding Affinity Can Influence Bone Marrow Suppression during Neoadjuvant Chemotherapy for Luminal A Type Breast Cancer

Table 1

Characteristics of the participants.

Variable	Number of cases (N = 175)
Median age (range)	54 (33–75)
Menopausal status
Premenopausal	31 (17.71%)
Postmenopausal	144 (82.29%)
TNM stage
TNM I-II	130 (74.29%)
TNM III-IV	45 (25.71%)
Efficacy of NAC
Effective (pCR + CR + PR)	147 (84.00%)
Invalid (SD + PD)	28 (16.00%)
Bone marrow suppression
Yes	112 (64.00%)
No	63 (36.00%)
Gastrointestinal toxicity
Yes	93 (53.14%)
No	82 (46.86%)

pCR, pathological complete response; CR, complete response; PR, partial response; SD, stable disease; PD, progressive disease; NAC, neoadjuvant chemotherapy.