BioMed Research International / 2019 / Article / Tab 1

Research Article

Functional Variant rs4442975 Modulating FOXA1 Binding Affinity Can Influence Bone Marrow Suppression during Neoadjuvant Chemotherapy for Luminal A Type Breast Cancer

Table 1

Characteristics of the participants.

VariableNumber of cases (N = 175)

Median age (range)54 (33–75)
Menopausal status
 Premenopausal31 (17.71%)
 Postmenopausal144 (82.29%)
TNM stage
 TNM I-II130 (74.29%)
 TNM III-IV45 (25.71%)
Efficacy of NAC
 Effective (pCR + CR + PR)147 (84.00%)
 Invalid (SD + PD) 28 (16.00%)
Bone marrow suppression
 Yes112 (64.00%)
 No63 (36.00%)
Gastrointestinal toxicity
 Yes93 (53.14%)
 No82 (46.86%)

pCR, pathological complete response; CR, complete response; PR, partial response; SD, stable disease; PD, progressive disease; NAC, neoadjuvant chemotherapy.