Functional Variant rs4442975 Modulating FOXA1 Binding Affinity Can Influence Bone Marrow Suppression during Neoadjuvant Chemotherapy for Luminal A Type Breast Cancer

Table 3

Association between rs4442975 and bone marrow suppression by NAC.

Variable	Bone marrow suppression
	No	Yes	OR (95% CI);
	N (%)	N (%)
rs4442975	61	105
TT	37 (60.66)	84 (80.00)	1.00
GT	22 (36.07)	21 (20.00)	0.39 (0.19–0.81); 0.011
GG	2 (3.28)	0	–
Dominant			0.36 (0.17–0.73); 0.005
Additive			0.38 (0.18–0.69); 0.003

and 95% CIs were calculated by unconditional logistic regression analysis after adjusting for age, smoking, alcohol use, and menopausal status.