Research Article

Does Pharmacological Treatment Reduce the Incidence of Lower Urinary Tract Symptoms (LUTS) after Transobturator Sling?

Table 2

The evolution of urgency in the course of the study.

VariableBaseline
n (%) [B]
Week 1
n (%) [W1]
Week 6
n (%) [W6]
Statistical analyses inside each group

Control group
(n=110) 
C
29 (26.4)66 (60.0)23 (20.9)B vs. W1, p <0.001
B vs. W6, NS
W1 vs. W6, p <0.001

Treatment group 1
(10 mg of solifenacin)
(n=114) 
S
35 (30.7)43 (37.7)11 (9.7)B vs. W1, NS
B vs. W6, p < 0.001
W1 vs. W6, p < 0.001

Treatment group 2
(50 mg of mirabegron)
(n=104) 
M
26 (25)43 (41.3)23 (22.1)B vs. W1, p<0.05
B vs. W6, NS
W1 vs. W6, p<0.005

Baseline: C vs. S (NS); C vs. M (NS); S vs. M (NS).
Week 1: C vs. S (p <0.001); C vs. M (p <0.001); S vs. M (NS).
Week 6: C vs. S (p<0.05); C vs. M (NS); S vs. M (p<0.05).