Research Article
Electrical Stimulation Activates Fibroblasts through the Elevation of Intracellular Free Ca2+: Potential Mechanism of Pelvic Electrical Stimulation Therapy
Figure 3
The effects of ES on Smads signaling and fibroblasts transformation. (a) The effect of smad2/3 translocation after ES and BAPTA-AM treatment. (b) Col III, α-SMA, and Smads signaling related protein expression after ES and BAPTA-AM treatment. P<0.001, NS: no significance compared with control. Every experiment was repeated for 3 times. Control: control group; ES: electrical stimulation group. BAPTA-AM: BAPTA-AM treatment group. B+ES: BAPTA-AM and electrical stimulation treatment group.
(a)
(b)