Determination of Haematological Reference Ranges in Healthy Adults in Three Regions in Ghana
Table 3
Haematological reference ranges of the study population stratified by regions.
Parameters
Ashanti Region (A)
Central Region (C)
Upper West Region (U)
p-value
Significant pairs
N
Median
Reference values
N
Median
Reference values
N
Median
Reference values
TWBC
145
6.03
3.56-12.64
168
5.32
3.12-10.47
171
5.34
3.35-9.86
<0.0001
A&C; A&U
RBC
145
4.61
3.34-6.07
168
4.53
2.99-7.7.01
171
4.76
3.54-6.67
0.083
-
Haemoglobin
145
13.10
9.09-16.51
168
12.70
7.49-20.71
171
14.30
9.57-18.33
<0.0001
A&C; C&U
HCT
145
39.40
26.83-52.41
168
38.60
25.72-63.12
170
42.76
30.51-57.00
<0.0001
A&C; C&U
MCV
145
86.30
66.25-102.75
168
84.60
61.73-104.31
171
90.00
70.03-102.61
<0.0001
A&C; C&U
MCH
145
28.60
21.55-33.20
168
28.40
19.18-34.28
171
30.00
22.36-34.71
<0.0001
A&C; C&U
MCHC
145
33.20
29.77-37.00
168
33.70
25.31-37.78
171
33.40
29.89-36.94
0.807
-
RDW-CV
144
14.00
11.96-19.89
166
14.45
11.82-33.03
171
13.90
11.70-17.77
0.001
C&U
Platelet
145
212.00
75.95-428.55
168
202.50
100.23-451.08
170
196.00
119.55-349.70
0.222
-
Neutrophils Abs
141
2.51
1.19-9.03
153
2.06
0.31-5.71
160
1.94
0.75-4.62
<0.0001
A&C; A&U
Neutrophils %
141
44.80
24.73-77.98
154
44.04
12.75-74.75
160
39.30
21.92-64.28
<0.0001
A&C; C&U
Lymphocytes Abs
141
2.53
0.87-5.80
167
1.93
0.52-4.02
160
2.34
0.93-4.02
<0.0001
A&C; A&U; C&U
Lymphocytes %
141
43.00
10.86-64.42
167
40.90
11.98-67.78
169
45.10
14.97-64.03
0.020
C&U
Monocytes Abs
141
0.51
0.24-1.30
167
0.46
0.12-0.99
169
0.51
0.19-0.89
0.018
A&U
Monocytes %
141
8.30
4.20-15.98
167
9.70
5.04-19.36
169
9.50
4.70-15.20
0.005
A&C; A&U
Eosinophils Abs
141
0.12
0.01-0.66
153
0.10
0.01-1.04
160
0.17
0.03-0.94
0.025
C&U
Eosinophils %
141
2.00
0.16-9.50
153
2.60
0.29-15.84
161
3.40
0.61-15.53
<0.0001
A&C; C&U
Basophils Abs
141
0.02
0.01-0.12
167
0.03
0.01-0.11
170
0.03
0.01-0.08
0.009
A&C
Basophils %
141
0.40
0.1-1.34
167
0.50
0.1-2.78
202
0.60
0.13-1.80
<0.0001
A&C; A&U
Kruskal-Wallis test was performed to compare Ashanti and Central and Upper West region, followed by Bonferroni post hoc test for pairwise analysis. P<0.05 was considered statistically significant (p-values of significant variable in bold print). TWBC: Total White Blood Cells; RBC: Red Blood Cells; HCT: Haematocrit; MCV: Mean Cell Volume, MCH: Mean Cell Haemoglobin; MCHC: Mean Cell Haemoglobin Concentration; RDW-CV: Red cell Distribution Width-Coefficient of Variation; Abs: Absolute.