The Level of Vitamin D in Children and Adolescents with Nonalcoholic Fatty Liver Disease: A Meta-Analysis

Table 2

Main characteristics of studies on continuous outcomes of vitamin D levels in NAFLD and controls, chronologically ordered.

Study	Year	Control			NAFLD			P-value
		Age; (mean ± SD)	No.; (Female/male)	25(OH)D (ng/ml); (mean ± SD)	Age; (mean ± SD)	No.; (Female/male)	25(OH)D (ng/ml); (mean ± SD)
Sezer et al.[17]	2016	12.60±3.10	53(38/15)	14.60±7.00	12.90±2.20	58(26/32)	16.60±6.20	0.113
Mohamed et al. [26]	2016	10.60±3.10	23(14/9)	41.98±14.52	11.13±2.70	47(28/19)	20.89±16.56	<0.001
Malespin et al. [27]	2015	12.90±2.90	382(193/189)	20.80±7.10	13.00±2.40	25(6/19)	16.50±6.40	0.024
Chang et al. [23]	2015	8.70±3.87	32(NR)	17.70±5.05	11.46±2.53	62(NR)	17.90±6.84	0.963
Yildiz et al. [24]	2014	11.00±2.80	43(24/19)	16.40±9.19	11.90±2.80	58(22/36)	12.60±6.52	0.005
Black et al.[28]	2014	17	838(381/457)	30.85±9.62	17	156(96/60)	26.84±8.81	<0.001
Nobili et al. [29]	2013	12.24±7.23	85(32/53)	29.04±5.81	13.00±2.96	73(NR)	19.30±6.70	<0.001
Pirgon et al. [25]	2013	12.48±1.60	72(NR)	43.96±19.97	12.80±0.80	45(NR)	29.50±18.40	<0.05

The levels of 25(OH)D were compared between NAFLD and control groups; SD: standard deviation; NR: not reported.