Exosomes May Be the Potential New Direction of Research in Osteoarthritis Management

Table 1

Exosome-derived miRNAs and lncRNAs in OA.

Names	Function	Mechanism	Ref
miR-100-5p	Maintains cartilage homeostasis	mTOR signaling pathway	[28]
miR-135b	Promotes chondrocyte proliferation and cartilage repair	miR-135b/SP1	[29]
miR-92a-3p	Regulates cartilage development and homeostasis	miR-92a-3p/Wnt5a	[30]
miRNA-95-5p	Regulates cartilage development and homeostasis	miRNA-95-5p-HDAC2/8	[9]
miR-140-5p	Enhances proliferation and migration of chondrocytes	miR-140-5p/RALA	[31]
KLF3-AS1	Promotes cartilage repair and chondrocyte proliferation	KLF3-AS1-miR-206/GIT1 axis	[41]
PCGEM1	As a biomarker	No mention	[42]