Phylogenetic Analysis and Screening of Antimicrobial and Antiproliferative Activities of Culturable Bacteria Associated with the Ascidian Styela clava from the Yellow Sea, China
Table 4
Antiproliferative activities against Bel 7402 cells of crude extracts from isolated bacterial strains associated with the ascidian Styela clava by MTT assay.
Test strains
IC50 (μg·mL−1)
Test strains
IC50 (μg·mL−1)
HQA008
177.22±12.51
HQB268
331.7±5.11
HQA018
356.35±3.32
HQB270
127.61±11.66
HQA038
355.55±7.54
HQB292
264.28±3.28
HQA054
391.01±5.24
HQB606
120.38±4.26
HQA802
432.97±6.21
HQB646
180.78±6.23
HQA810
183.24±7.17
HQB650
343.61±7.49
HQB216
295.46±8.92
HQB653
179.73±3.57
HQB237
0.44±0.09
HQB667
291.69±11.34
HQB243
161.06±12.54
HQB670
400.92±4.50
HQB246
187.83±10.28
HQB811
374.7±3.41
HQB251
417.54±4.03
HQB823
86.77±5.92
HQB252
263.21±3.10
HQB824
191.61±11.22
HQB255
276.44±6.31
HQB827
282.84±12.23
HQB265
165.87±7.62
HQF015
321.95±6.42
HQB266
414.39±4.67
Only the bacterial strains with antiproliferative activity IC50⩽500 μg·mL−1 were listed. Data is expressed as mean ± SE of three or more experiments.