Phylogenetic Analysis and Screening of Antimicrobial and Antiproliferative Activities of Culturable Bacteria Associated with the Ascidian Styela clava from the Yellow Sea, China
Table 5
Antiproliferative activities against HeLa cells of crude extracts from isolated strains associated with the ascidian Styela clava by MTT assay.
Test strains
IC50 (μg·mL−1)
Test strains
IC50 (μg·mL−1)
HQA018
471.42±4.43
HQB293
122.05±1.68
HQA024
390.18±8.15
HQB295
450.54±3.72
HQA037
346.96±8.27
HQB299
348.12±6.84
HQA802
422.5±3.11
HQB602
248.85±4.28
HQA806
25.88±3.57
HQB603
376.95±5.76
HQA809
160.44±5.97
HQB606
109.82±7.61
HQB218
206.47±3.69
HQB620
453.36±3.02
HQB221
150.78±10.23
HQB624
104.04±4.29
HQB223
181.03±5.14
HQB627
254.68±3.86
HQB225
288.1±5.22
HQB628
339.46±6.85
HQB226
267.55±4.21
HQB646
113.97±7.32
HQB227
458.09±6.33
HQB650
218.64±7.19
HQB230
260.71±7.25
HQB653
213.13±4.55
HQB231
155.03±5.45
HQB663
308.37±4.03
HQB232
205.97±4.86
HQB666
207.91±5.25
HQB239
298.21±4.11
HQB667
129.77±5.28
HQB242
295.53±6.25
HQB805
332.63±4.37
HQB244
261.23±7.77
HQB811
338.56±6.32
HQB246
187.35±6.25
HQB813
278.38±7.74
HQB255
204.81±10.25
HQB823
193.10±8.31
HQB266
302.2±3.12
HQB824
55.84±7.80
HQB267
346.18±7.29
HQB825
202.05±7.36
HQB268
373.57±6.27
HQB827
42.57±5.68
HQB279
150.01±11.23
HQB828
193.42±7.38
HQB281
61.74±4.50
HQB835
158.29±12.23
HQB287
66.25±8.37
HQB837
265.57±8.52
HQB292
101.32±7.54
Only the bacterial strains with antiproliferative activity IC50⩽500 μg·mL−1 were listed. Data is expressed as mean ± SE of three or more experiments.
