Neutrophil-to-Lymphocyte Ratio in Ovarian Cancer Patients with Low CA125 Concentration

Table 5

Characterization of the different diagnostic methods for different study groups.

	Positive#	Negative#	Total	Sensitivity	Specificity	PPV	NPV
Entire patient group
CA125>35 U/ml
Positive	152	0	152	87.9%	100%	100%	76.9%
Negative	21	70	91
Total	173	70	243
CA125 >24.55 U/ml and NLR>3.00
Positive	66	0	66	38.2%	100%	100%	39.5%
Negative	107	70	177
Total	173	70	243
CA125 >24.55 U/ml or NLR>3.00
Positive	160	15	175	92.5%	78.6%	91.4%	80.9%
Negative	13	55	68
Total	173	70	243
Low concentration patient group
CA125>35 U/ml
Positive	0	0	0	0%	0%	0%	76.9%
Negative	21	70	91
Total	21	70	91
CA125 >7.65 U/ml and NLR>1.72
Positive	11	23	34	52.4%	67.1%	32.4%	82.5%
Negative	10	47	57
Total	21	70	91
CA125 >7.65 U/ml or NLR>1.72
Positive	21	61	82	100%	12.9%	25.6%	100%
Negative	0	9	9
Total	21	70	91

PPV: positive predictive value; NPV: negative predictive value; #: results based on pathology test.