Research Article
Vitamin D Receptor Gene Polymorphisms and Autoimmune Thyroiditis: Are They Associated with Disease Occurrence and Its Features?
Table 4
Linkage disequilibrium between VDR gene polymorphisms.
| | Locus 1 | Locus 2 | D’ (CI) | LOD | r2 |
| | rs731236 (TaqI) | rs7975232 (ApaI) | 1.0 (0.94-1.0) | 32.85 | 0.73 | | rs731236 (TaqI) | rs1544410 (BsmI) | 0.95 (0.89-0.98) | 42.13 | 0.90 | | rs731236 (TaqI) | rs2228570 (FokI) | 0.05 (0.0-0.26) | 0.05 | 0.00 | | rs731236 (TaqI) | rs11568820 (Cdx2) | 0.50 (0.18-0.73) | 1.51 | 0.05 | | rs7975232 (ApaI) | rs1544410 (BsmI) | 0.98 (0.9-1.0) | 30.17 | 0.70 | | rs7975232 (ApaI) | rs2228570 (FokI) | 0.06 (0.0-0.24) | 0.08 | 0.00 | | rs7975232 (ApaI) | rs11568820 (Cdx2) | 0.59 (0.21-0.8) | 1.59 | 0.05 | | rs1544410 (BsmI) | rs2228570 (FokI) | 0.06 (0.0-0.26) | 0.06 | 0.00 | | rs1544410 (BsmI) | rs11568820 (Cdx2) | 0.44 (0.14-0.68) | 1.29 | 0.04 | | rs2228570 (FokI) | rs11568820 (Cdx2) | 0.12 (0.01-0.52) | 0.05 | 0.00 |
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D’, value of D prime between the loci; LOD, likelihood odds ratio;
r2, correlation coefficient between two loci; CI, confidence interval.
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