Establishment and Verification of Prognostic Nomograms for Patients with Gastrointestinal Stromal Tumors: A SEER-Based Study
Table 2
Multivariate analysis of overall survival and cancer-specific survival in the training cohort.
Variable
OS
CSS
HR
95% CI
P
HR
95% CI
P
Age at diagnosis, years
0.020
0.040
<50
ref
ref
50-64
1.393
1.143 to 1.781
1.477
1.034 to 1.735
65-79
1.309
1.098 to 1.816
1.568
1.155 to 2.199
⩾80
1.719
1.028 to 2.875
1.639
1.265 to 2.207
Gender
0.000
0.008
Female
ref
ref
Male
1.397
1.230 to 1.585
1.269
1.063 to 1.516
Race
0.236
0.401
White
ref
ref
Black
1.380
0.870 to 2.190
1.485
0.772 to 2.857
Others
1.155
0.922 to 1.447
1.153
0.836 to 1.589
Tumor size
0.000
0.000
⩽ 5 cm
ref
ref
5.1-10 cm
2.596
2.135 to 3.156
1.686
1.313 to 2.164
> 10 cm
2.314
1.891 to 2.832
1.654
1.279 to 2.139
Location
0.001
0.000
Stomach
ref
ref
Small intestine
1.174
1.017 to 1.355
1.393
1.141 to 1.700
Colon/Rectum
1.115
0.847 to 1.467
1.282
0.884 to 1.861
Others
1.679
1.293 to 2.179
1.920
1.348 to 2.734
Surgery of primary
0.000
0.000
No surgery of primary tumor
ref
ref
Surgery of primary tumor
0.327
0.286 to 0.375
0.242
0.201 to 0.292
Others includes American Indian/Alaskan Native and Asian/Pacific Islander; Others includes esophagus, appendix, and peritoneum. Abbreviations: OS, overall survival; CSS, cancer-specific survival; HR, hazard ratio; CI, confidence interval; ref, reference.
