Evaluation of Objective Signs and Subjective Symptoms of Dry Eye Disease in Patients with Inflammatory Bowel Disease

Table 1

Characteristics and comparison of control persons with CD and UC patients presented as mean±SD. CD: Crohn’s disease; UC: ulcerative colitis; tBUT: tear breakup time; LIPCOF: lid parallel conjunctival folds; OSDI: ocular surface disease index; Co: control.

	Control	CD	UC	p: Co vs CD
				p: Co vs UC
Age; (years)	48.51 ± 15.92	42.26 ± 12.36	46.38 ± 2.75	0.2015
				0.6071
Disease duration; (years)	-	13.9 ± 7.98	12 ± 7.52	(CD vs UC)
				0.4249
tBUT; (s)	11.23 ± 2.98	7.43 ± 5.16	7.52 ± 3.59	0.0075
				0.0214
Schirmer I test; (mm/5 min)	13.19 ± 4.86	9.11 ± 7.58	8.52 ± 6.13	0.0328
				0.0112
Lissamine Green; score	0.59 ± 0.63	1.14 ± 0.91	1.12 ± 0.99	0.0282
				0.2758
LIPCOF; grading	0.51 ± 0.52	1.31 ± 0.82	1.19 ± 0.94	0.0065
				0.0219
OSDI; total score	10.88 ± 5.54	30.59 ± 16.68	24.67 ± 3.48	0.0001
				0.0550