Selectivity of Dietary Phenolics for Inhibition of Human Monoamine Oxidases A and B

Table 1

Selectivity of phenolic compounds for MAO-A and MAO-B.

	MAO-A		MAO-B		Selectivity Index
	IC50 (µM)	Hill coefficient	IC50 (µM)	Hill coefficient
curcumin	12.9 ± 1.3	2.0 ± 0.4	6.30 ± 0.11	1.7 ± 0.1	0.488
guaiacol	131 ± 6	1.0	322 ± 27	1.0	2.46
isoeugenol	3.72 ± 0.20	1.2 ± 0.1	102 ± 5	2.4 ± 0.3	27.4
pterostilbene	13.4 ± 1.5	1.7 ± 0.3	0.138 ± 0.013	1.0	0.0103
resveratrol	0.313 ± 0.008	1.1 ± 0.0	15.8 ± 1.3	1.6 ± 0.2	50.5
zingerone	16.3 ± 1.1	1.0