Amino Acid Biosignature in Plasma among Ischemic Stroke Subtypes

Table 2

Figures of merit for PLS-DA models to discriminate chronic ischemic stroke from control/healthy plasma samples.

Parameters	Model #1	Model #2
Sensitivity (training set)	0.961	0.902
Specificity (training set)	0.909	0.818
EFR (training set)	0.870	0.870
Sensitivity (test set)	0.955	0.955
Specificity (test set)	0.800	0.800
EFR (test set)	0.755	0.720
N° of LV	3	2
Variance in X	66.02%	79.64%
Variance in Y	63.63%	31.62%
Q^2	0.478	0.176
AUROC	0.800	0.800

Considering the detection of two control samples as outliers by the studentized y residuals at 95% confidence level, the EFR is 0.961 and 0.955 for the training and test sets, respectively.