Research Article
Evaluation of the Efficacy of a Recombinant Adenovirus Expressing the Spike Protein of Porcine Epidemic Diarrhea Virus in Pigs
Table 1
Experimental design of pig vaccination and challenge.
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aEach group contained five 4-week-old weaned piglets. b–dPigs in these three groups were vaccinated intramuscularly with 1010 PFU/mL Ad-blank, 1010 PFU/mL rAd-PEDV-S, and 2 mL of commercial PEDV inactivated vaccine (inactivated virus of the genotype GIIb strain; virus titer before inactivation ≥ 107 TCID50), respectively. eEach pig was challenged orally with a virus suspension containing 2 × 105 TCID50 highly virulent genotype GIIb PEDV strain CH/HNPJ/2017. Dpv: days post vaccination; IM: intramuscularly. |