Relationship between Serum Vitamin D and Calcium Levels and Vitamin D Receptor Gene Polymorphisms in Colorectal Cancer

Table 3

Correlation between different genotypes of TaqI SNP with the expression of total vitamin D, 25(OH)D₃, and calcium serum levels in patients and controls.

Biochemical test	Patients (n=50)			Controls (n=50)			P value
	Frequency ()			Frequency ()
	TT	Tt	tt	TT	Tt	tt
	24 (48%)	20 (40%)	6 (12%)	46 (92%)	3 (6%)	1 (2%)
Total vitamin D (nmol/L)	106.20±18.12	71.87±8.06	72.51±9.89	143.10±10.92	134.90±45.63	168.10±0.0	0.0008
P value	0.76			0.83
25(OH)D3 (nmol/L)	36.29±3.21	29.35±2.59	33.33±5.49	38.04±2.14	34.33±8.84	29.00±0.0	0.39
P value	0.38			0.74
Calcium (mmol/L)	2.23±0.022	2.19±0.044	2.26±0.023	2.31±0.014	2.30±0.051	2.40±0.0	0.0042
P value	0.54			0.51

P value was calculated by Kruskal-Wallis test with Dunn’s multiple comparison.