Relationship between Serum Vitamin D and Calcium Levels and Vitamin D Receptor Gene Polymorphisms in Colorectal Cancer
Table 4
Correlation between different genotypes of BsmI SNP with the expression of total vitamin D, 25(OH)D3, and calcium serum levels in patients and controls.
Biochemical test
Patients (n=50)
Controls (n=50)
P value
Frequency ()
Frequency ()
BB
Bb
bb
BB
Bb
bb
20 (40%)
22 (44%)
8 (16%)
6 (12%)
28 (56%)
16 (32%)
Total vitamin D (nmol/L)
107.40±16.58
79.32±14.77
69.30±9.71
124.0±23.87
130.4±14.40
172.4±16.54
< 0.0001
P value
0.25
0.07
25(OH)D3 (nmol/L)
36.50±3.85
30.77±2.58
31.38±3.27
36.17±4.60
38.86±2.46
36.06±4.45
0.48
P value
0.58
0.79
Calcium (mmol/L)
2.23±0.021
2.18±0.041
2.27±0.035
2.34±0.013
2.31±0.021
2.31±0.023
0.0031
P value
0.35
0.57
P value was calculated by Kruskal-Wallis test with Dunn’s multiple comparison.