Relationship between Serum Vitamin D and Calcium Levels and Vitamin D Receptor Gene Polymorphisms in Colorectal Cancer

Table 4

Correlation between different genotypes of BsmI SNP with the expression of total vitamin D, 25(OH)D₃, and calcium serum levels in patients and controls.

Biochemical test	Patients (n=50)			Controls (n=50)			P value
	Frequency ()			Frequency ()
	BB	Bb	bb	BB	Bb	bb
	20 (40%)	22 (44%)	8 (16%)	6 (12%)	28 (56%)	16 (32%)
Total vitamin D (nmol/L)	107.40±16.58	79.32±14.77	69.30±9.71	124.0±23.87	130.4±14.40	172.4±16.54	< 0.0001
P value	0.25			0.07
25(OH)D3 (nmol/L)	36.50±3.85	30.77±2.58	31.38±3.27	36.17±4.60	38.86±2.46	36.06±4.45	0.48
P value	0.58			0.79
Calcium (mmol/L)	2.23±0.021	2.18±0.041	2.27±0.035	2.34±0.013	2.31±0.021	2.31±0.023	0.0031
P value	0.35			0.57

P value was calculated by Kruskal-Wallis test with Dunn’s multiple comparison.