Scientific Validation of Ethnomedicinal Use of Ipomoea batatas L. Lam. as Aphrodisiac and Gonadoprotective Agent against Bisphenol A Induced Testicular Toxicity in Male Sprague Dawley Rats
Table 5
Appraisal of reforms in hormonal levels by I. batatas.
Sample
Testosterone (ng/ml)
FSH (mIU/ml)
LH (mIU/ml)
Estradiol (ng/ml)
Control
4.41±0.12
11.27±0.52
3.14±0.23
18.02±0.14
Vehicle (10% DMSO)
4.33±0.09
10.93±0.75
3.29±0.33
19.14±0.17
Sildenafil (10 mg/kg)
6.89±0.14
16.68±0.89
5.85±0.28
18.10±0.22
BPA (50 mg/kg)
1.47±0.06
5.71±0.31
1.41±0.14
26.19±0.16
IPT- EA (300 mg/kg)
6.05±0.11
14.66±0.82
4.74±0.32
17.99±0.04
IPT-M (300 mg/kg)
5.54±0.15
14.14±0.54
4.34±0.23
18.88±0.11
IPA-EA (300 mg/kg)
6.81±0.10
17.18±0.91
5.79±0.13
18.33±0.16
IPA-M (300 mg/kg)
5.78±0.12
14.05±0.43
4.45±0.18
19.26±0.28
BPA+IPT-EA (300 mg/kg)
3.98±0.06
9.21±0.35
2.71±0.12
21.88±0.18
BPA+IPT-EA (150 mg/kg)
3.69±0.12
8.31±0.22
2.38±0.10
23.18±0.23
BPA+IPT-M (300 mg/kg)
3.82±0.05
8.59±0.18
2.54±0.09
22.14±0.11
BPA+IPT-M (150 mg/kg)
3.56±0.10
7.87±0.29
2.31±0.15
23.21±0.18
BPA+IPA-EA (300 mg/kg)
4.22±0.09
10.2±0.27
3.09±0.13
20.07±0.17
BPA+IPA-EA (150 mg/kg)
3.93±0.16
9.22±0.36
2.59±0.12
21.28±0.08
BPA+IPA-M (300 mg/kg)
3.87±0.11
9.04±0.42
2.65±0.10
21.39±0.12
BPA+IPA-M (150 mg/kg)
3.58±0.12
8.01±0.35
2.35±0.09
22.78±0.31
FSH, follicle stimulating hormone and LH, luteinizing hormone. All the data are represented as Mean±SD (n=7), means with different superscript letters in a column specify significant difference at P < 0.05. IPA, I. batatas aerial and IPT, I. batatas tuber extract.
