BioMed Research International / 2019 / Article / Tab 2

Research Article

Amides Derived from Vanillic Acid: Coupling Reactions, Antimicrobial Evaluation, and Molecular Docking

Table 2

Effects of amide 7 MIC against C. guilliermondii, in the presence or absence of a protective osmotic (sorbitol 0.8 M) as well as in the presence or absence of ergosterol.

Concentration (μmol/mL)Candida guilliermondii
(207)
No sorbitolWith sorbitolNo ergosterolWith ergosterol

3.68-+--
1.84-+-+
0.92-+-+
0.46-+-+
0.23++++
0.11++++
Caspofungin0.3 μmol/mL4.5 μmol/mL-
Nistatin-0.00043 μmol/mL0.26 μmol/mL

+:microorganism growth. -: no microorganism growth.

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