Clinical Study

Effects of Serum Cytochrome c on Contrast-Induced Nephropathy in Patients with ST-Elevation Myocardial Infarction Undergoing Percutaneous Coronary Intervention

Table 1

Baseline clinical characteristics between patients with CIN and those without CIN.

VariablesCIN(n=29)Non-CIN(n=211)P value

Male,n (%)18 (62.1)161 (76.3)0.099
Age (years)71.07±13.7763.06±12.70.002
Smoking,n (%)14 (48.3)118 (55.9)0.438
Hypertention,n (%)24 (82.8)126 (59.7)0.016
Diabetes mellitus,n (%)13 (44.8)50 (23.7)0.015
Systolic BP (mm Hg)127.21±22.72128.39±22.020.585
Diastolic BP (mm Hg)74.59±13.276.65±14.30.519
Heart rate (t/min)82.59±15.9980.33±17.40.486
LV (cm)5.04±0.494.83±0.60.029
LVEF (%)0.47±0.120.53±0.110.02
Contrast dose (mL)109.66±23.22105.17±15.720.152
Hydration,n (%)16 (55.2)52 (24.6)0.001
Number of diseased vessels, n3.1±1.592.78±1.260.336
Medication,n (%)
Aspirin27 (93.1)203 (96.2)0.433
Ticagrelor29 (1)210 (99.5)0.71
-Blocker24 (82.8)175 (82.9)0.981
ACEI/ARB11 (37.9)134 (63.5)0.008
CCB4 (13.8)16(7.6)0.257
Statin28 (96.6)203 (96.2)0.927
Diuretics16 (55.2)65 (30.8)0.009
Hospitalization (days)13.62±9.0410.02±10.170.009
Hospitalization costs (RMB)65245.52±30207.0659278.88±45699.020.127

Data were presented as means ± standard deviation or number(%). BP, blood pressure; LV, left ventricular; LVEF, left ventricular ejection fraction; ACEI, angiotensin-converting enzyme inhibitor; ARB, angiotensin receptor blocker; CCB, calcium channel blocker.