The Effectiveness of Ultrasound-Guided Steroid Injection Combined with Miniscalpel-Needle Release in the Treatment of Carpal Tunnel Syndrome vs. Steroid Injection Alone: A Randomized Controlled Study
Table 2
Outcome measurements of BCTQ, DML, CMAP, SNAP, SNCV, and CSA among patients at different time points.
Baseline
4 weeks
12 weeks
F
P
BCTQ-SSS
Group A
3.10±0.32
2.34±0.21
1.84±0.21
Group (G)
2.892
0.096
Group B
3.00±0.25
2.47±0.25
2.06±0.23
Time (T)
292.617
<0.001
G×T
6.690
0.002
Mauchly’s Sphericity test W=0.882 (P=0.067)
BCTQ-FSS
Group A
3.10±0.25
2.46±0.22
1.80±0.35
Group (G)
2.634
0.112
Group B
3.00±0.25
2.53±0.24
2.08±0.27
Time (T)
235.033
<0.001
G×T
7.144
0.001
Mauchly’s Sphericity test W=0.987 (P=0.754)
CMAP (mV)
Group A
9.4±1.2
9.7±1.2
12.2±1.3
Group (G)
0.259
0.613
Group B
9.5±1.1
9.9±1.2
11.3±1.1
Time (T)
462.702
<0.001
G×T
26.119
<0.001
Mauchly’s Sphericity test W=0.902 (P=0.110)
DML (ms)
Group A
5.2±0.3
4.9±0.3
4.5±0.4
Group (G)
11.214
0.002
Group B
5.4±0.3
5.1±0.3
4.7±0.4
Time (T)
51.852
<0.001
G×T
0.094
0.910
Mauchly’s Sphericity test W=0.899 (P=0.100)
SNAP (μV)
Group A
12.1±1.8
14.1±2.6
16.3±3.5
Group (G)
0.829
0.368
Group B
12.0±1.6
13.5±2.7
15.4±2.7
Time (T)
34.857
<0.001
G×T
0.371
0.691
Mauchly’s Sphericity test W=0.963 (P=0.448)
SNCV (m/s)
Group A
38.6±3.8
42.2±2.8
46.5±2.5
Group (G)
0.283
0.597
Group B
39.5±3.2
42.1±2.2
44.7±3.2
Time (T)
99.794
<0.001
G×T
4.292
0.017
Mauchly’s Sphericity test W=0.909 (P=0.128)
CSA (mm2)
Group A
13.3±1.4
12.5±1.4
10.8±1.1
Group (G)
0.477
0.493
Group B
13.1±1.5
12.7±1.4
11.6±1.2
Time (T)
108.913
<0.001
G×T
7.251
0.001
Mauchly’s Sphericity test W=0.969(P=0.503)
Note. Group A was steroid injection combined with MSN release group. Group B was steroid injection group. Values were described using Mean ± Standard Deviation (SD). Comparisons between week 4 follow-up and baseline and week 12 follow-up and baseline, respectively. P < 0.05, P < 0.01, and P < 0.001. Comparisons between group A and group B at corresponding time points. P < 0.05, P < 0.01, and P < 0.001. Abbreviations. BCTQ-SSS: the symptom severity scale of Boston carpal tunnel questionnaire; BCTQ-FSS: the functional status scale of Boston carpal tunnel questionnaire; CMAP: compound muscle action potential; DML: distal motor latency; SNAP: sensory nerve action potential; SNCV: sensory nerve conduction velocity; CSA: cross-sectional area of the median nerve.
