Research Article

Influences of Corydalis decumbens on the Activities of CYP450 Enzymes in Rats with a Cocktail Approach

Table 2

Precision, accuracy, extraction recovery, and matrix effect of five probes in rat plasma (n=6).

Analytes Concentration added (ng/mL) Intra-day Inter-dayRecovery
(%)
Matrix effect
(%)
RSD (%) RE (%) RSD (%) RE (%)

Phenacetin54.932.104.90-0.1983.5098.41
1007.021.698.022.7884.7197.97
5002.42-1.395.06-0.9387.35102.59
Metoprolol510.85-0.889.74-0.3988.9895.26
1008.27-3.419.16-2.7490.7697.67
5004.701.865.900.4287.2497.27
Midazolam2.58.014.408.820.6885.6295.46
258.60-0.489.22-2.2184.0296.47
1005.650.777.56-0.2887.4897.82
Omeprazole55.69-0.586.911.7285.9398.78
506.454.285.15-2.1888.9395.91
5002.256.242.901.6686.95100.34
Tolbutamide1002.41-4.448.123.9785.8298.94
5004.171.874.66-0.7387.4395.97
50003.280.414.23-1.1986.8599.18