Xiao-Qing-Long Tang Prevents Cardiomyocyte Hypertrophy, Fibrosis, and the Development of Heart Failure with Preserved Ejection Faction in Rats by Modulating the Composition of the Gut Microbiota

Figure 3

XQLT improves echocardiographic indexes, protects cardiac function, and ameliorates organ weight changes. Echocardiographic indexes such as the (a) wall thickness (WT), (b) left ventricular mass (LV mass), (c) left ventricular diastolic diameter (LVDd), and (d) left ventricular ejection fraction (LVEF) were assessed using an M5 Vet Veterinary Ultrasound system. The (e) heart weight/body weight and (f) lung weight/body weight ratios are shown. (g) NT-proBNP was assessed by ELISA. The data are presented as the mean±SD (n=6 rats per group) p < 0.05 and p < 0.01 compared with the NS group; p <0.05 and p <0.01 compared with the HS group.

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