Advances in Gut Microbiota of Viral Hepatitis Cirrhosis

Table 1

Microbiota in HBV/HCV cirrhotic patients vs controls.

Investigators	N	HBV/HCV-related cases (n)	Changed microbiota
			Increased	Decreased
Chen et al. [32]	58	24 HBV-related	Firmicutes, Veillonella	Proteobacteria, Neisseria
			Megasphaera, Dialister	Haemophilus
			Atopobium, Prevotella	SR1 genera incertae sedis
Qin et al. [33]	181	99 HBV-related	Proteobacteria, Fusobacteria	Bacteroidetes, Bacteroides
			Veillonella, Streptococcus	Eubacterium, Alistipes
			Clostridium, Prevotella
Xu et al. [34]	47	16 HBV-related	B. dentium	B. catenulatum, B. infantis
				B. bifidum
Ponziani et al. [35]	24	12 HCV-related	Proteobacteria, Staphylococcaceae	Methanobacteriaceae
			Veillonellaceae, Enterobacteriaceae	Methanobrevibacter
			Corynebacteriaceae, Dialister
			Staphylococcus, Micrococcaceae
			Eubacterium, Enterococcus
Heidrich et al. [36]	145	38 HCV-related	Alloprevotella, Lactobacillus	Clostridium IV, Bilophila
			Streptococcus, Veillonella	Mitsuokella, Victivallis
			Haemophilus, Akkermansia	Butyricimonas
Aly et al. [37]	15	7 HCV-related	Bacteroidetes, Prevotella	Ruminococcus, Clostridium
			Acinetobacter, Faecalibacterium	Parabacteroides
			Phascolarctobacterium, Veillonella
Bajaj et al. [38]	244	119 HCV-related	Staphylococcaceae, Enterococcaceae	Bacteroidaceae, Prevotellaceae
			Streptococcaceae	Clostridiales XIV
			Enterobacteriaceae	Ruminococcaceae, Veillonellaceae

N means the total number of patients in the study, which included healthy controls and those with HBV- or HCV-related cirrhosis.