Research Article

P4HB, a Novel Hypoxia Target Gene Related to Gastric Cancer Invasion and Metastasis

Figure 3

P4HB was identified as a target gene of HIF-1α. (a) The Protein-protein interaction (PPI) network of the upregulated DEGs in SCR-AGS (edge size was according to the degree, and color was according to the number of directed edges; red=30, yellow=15, and green=0). (b) The module contained P4HB. (c) The Kaplan-Meier curves of patients with GC based on expression of P4HB in the Kaplan-Meier plotter database; patients with low expression of P4HB showed a better survival rate (P = 0.0057).