Snake-Eyes Appearance on MRI Occurs during the Late Stage of Hirayama Disease and Indicates Poor Prognosis

Table 2

Demographics and imaging parameters of 60 patients with HD.

Characteristic	SEA	Non-SEA	Univariate analysis	Multivariate analysis
				OR	95 CI	p-value
Age (y)	24.40 ± 1.21	18.70 ± 0.46	p < 0.0001 (t = 4.395)
Sex (no. [%])
Male	28 (93.3)	30 (100)
Female	2 (6.7)	0 (0)	p = 0.4915
Duration (m)	72.80 ± 10.93	21.07 ± 3.31	p < 0.0001 (t = 4.532)	0.960	0.928-0.993	0.016
Atrophy side (no. [%])
Left	10	8
Right	11	16
Bilateral	9	6	P = 0.4172 (χ^2 = 1.748)
Hoffmann sign (no. [%])
(-)	14 (46.7)	28 (93.3)		1 (ref)
(+)	16 (53.3)	2 (6.7)	p < 0.0001	7.200	1.197-43.310	0.031
Knee-jerk reflex (no. [%])
(++)	11 (36.7)	23 (76.7)
(+++)/(++++)	19 (63.3)	7 (23.3)	p = 0.0038
Atrophy (%)	41.93 ± 1.95	32.22 ± 1.93	p = 0.0008 (t = 3.534)	0.917	0.843-0.998	0.044
Shifting (%)	52.76 ± 1.82	56.61 ± 1.15	p = 0.0792 (t = 1.786)