New Platinum(IV) and Palladium(II) Transition Metal Complexes of s-Triazine Derivative: Synthesis, Spectral, and Anticancer Agents Studies

Table 5

IC₅₀ activity of the free ligands and its Pt(IV) complexes.

Against human colon cancer cell lines
Concentration (μg/mL)	Viability (%)
	L^1	1	L^2	2	L^3	3	L^4	4
100	65	66	61	72.7	55.3	6.4	35.5	44.6
50	70	67.8	64.4	81.7	60	31.8	41.4	56.6
10	72	70	69.3	82.5	65	62.9	66.8	71.5
IC50	170	461	277	259	162.8	27	50.7	79
Against human lung cancer A549 cell lines
Concentration (μg/mL)	Viability (%)
	L^1	1	L^2	2	L^3	3	L^4	4
150	82.4	100	96	100	100	44.6	100	77.7
100	83.4	100	98.7	100	100	61.7	100	100
50	86	100	100	100	100	66.5	100	100
10	98.7	100	100	100	100	100	100	100
IC50	431.4	-	1305.7	-	-	128	-	212