DMBA-Induced Oral Carcinoma in Syrian Hamster: Increased Carcinogenic Effect by Dexamethasone Coexposition

Table 1

Frequency of histopathological lesions observed at each time of sacrifice.

Weeks of DMBA exposure	Number of animals with histopathological lesions
	LymSubInf		EXO		ULC		NEC		DYS		PAP		SCC
	w/o DM	w/DM	w/o DM	w/DM	w/o DM	w/DM	w/o DM	w/DM	w/o DM	w/DM	w/o DM	w/DM	w/o DM	w/DM
3	1	2	—	2	—	—	—	—	—	—	—	—	—	—
6	1	1	—	1	—	—	1	1	—	—	—	—	—	—
9	2	1	2	—	—	—	1	1	—	1	—	—	—	—
12	2	—	2	—	—	—	2	1	—	1	—	1	—	—
15	2	1	2	1	1	2	1	2	1	2	1	2	1	2

w/o DM: without dexamethasone; w/DM: with dexamethasone; LymSubInf = lymphocytic submucosal infiltration; EXO = exocytosis; ULC = ulceration; NEC = necrosis; DYS = dysplasia; PAP = papilloma; SCC = squamous cell carcinoma.